Rennie Sugar Free, 48 Tablets

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Long term use of high doses can cause high blood levels of calcium and magnesium, especially in people with kidney conditions. Symptoms of this may include nausea, vomiting, upset stomach, constipation, diarrhoea, tiredness, muscular weakness, headache, kidney problems and impaired sense of taste. Many women suffer from both heartburn (acid reflux) and indigestion during pregnancy and it tends to become more common as the pregnancy progresses. In fact, by the third trimester, nearly three-quarters of pregnant women can suffer from heartburn. We take a look at the causes and symptomsof heartburn during pregnancy and explore a few options for treating this uncomfortable condition. Causes of heartburn in pregnancy Especially in patients with impaired renal function, prolonged use of high doses can result in hypermagnesaemia or hypercalcaemia and alkalosis which may give rise to gastric symptoms and muscular weakness (see below).

It has been shown that antacids which contain calcium or magnesium may form complexes with certain substances e.g. antibiotics (such as tetracyclines and quinolones), and cardiac glycosides (e.g. digoxin), bisphosphonates, dolutegravir, levothyroxine, and eltrombopag, resulting in decreased absorption. This should be borne in mind when concomitant administration is considered.

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Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity. If you are taking any of the following medicines speak to your doctor or pharmacist before taking Rennie Sugar Free because it can affect how these medicines work. Rennie should not be used in patients with hypercalciuria (see also section 4.3). Prolonged use increases the risk of formation of renal calculi.

The listed adverse drug reactions are based on spontaneous reports, thus an organisation according to CIOMS III categories of frequency is not possible.

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The stated dose should not be exceeded. If, after 14 days of treatment, symptoms persist or only partly disappear the patient should consult a doctor. Thiazide diuretics reduce the urinary excretion of calcium. Due to an increased risk of hypercalcaemia, serum calcium should be regularly monitored during concomitant use of thiazide diuretics. In case of more frequent or severe pain, the dose may be increased for a short period, up to 10 tablets per day.