Organic Lions Mane Mushroom 1500mg - 120 High Strength Vegan Capsules (Not Powder) - Lions Mane Supplement with Organic Black Pepper - Made in The UK by Nutravita

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For a cognitive boost without the potential jitters, Mind Lab Pro® may be the nootropic for your focus needs. This natural, caffeine-free formula boasts 11 premium ingredients, including 500 milligrams of organic lion's mane mushroom. Their patented NutriCaps® are prebiotic capsules that don't contain gelatin and therefore are vegan and vegetarian-friendly. Research shows (3) that Hericium Erinaceus fights diabetes and has antihyperglycemic and anti-lipidemic benefits, which can lower blood sugar and cholesterol levels. However, most people with diabetes use other pharmaceutical drugs to maintain healthy blood sugar levels. Yao, W., Zhang, J. C., Dong, C., Zhuang, C., Hirota, S., Inanaga, K., & Hashimoto, K. (2015, September). Effects of amycenone on serum levels of tumor necrosis factor-α, interleukin-10, and depression-like behavior in mice after lipopolysaccharide administration [Abstract]. Pharmacology, Biochemistry, and Behavior, 136, 7–12 Research was carried out on this mushroom powder using rats in 2005, and the findings unearthed several medicinal substances present in Hericium Erinaceus. The substances included palmitic acid, threitol and D-arabinitol. A study of these substances found them to be responsible for reducing blood sugar and regulating lipid levels in the blood. Evidence also suggested this mushroom has a wide range of antioxidants. Lion’s mane may help digestive health by fighting inflammation, which could be beneficial for people with inflammatory bowel disease (IBD). The mushroom may also boost immune function and encourage the growth of good bacteria in the gut.

Research also suggests that lion’s mane may protect nerves from disease or decline, according to a 2015 abstract in the Journal of Agricultural and Food Chemistry. The same study concludes the mushroom displays additional health-promoting benefits, such as: By prioritising native strains we are avoiding the spread of billions of spores that come from commercial mushroom strains that have been selected specifically for their ability to grow fast and fruit heavily, and will therefore easily outcompete a lot of the native strains we have growing around the farm. Triple Extracted, 1: 4 Ratio (Super Strength)

Liang. B., Guo, Z., Xie, F., & Zhai, A. (2013, October 3). Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complementary and Alternative Medicine, 2013(13), 253 To treat Parkinson's disease with Lion's mane , start with the lowest dosage of 250 mg daily and slowly increase your dosage to about 3,000 mg. When increasing your dosage, note how your body behaves, stopping at the point where you get maximum relief from the symptoms of Parkinson's. Lai PL, Naidu M, Sabaratnam V, Wong KH, David RP, Kuppusamy UR, Abdullah N, Malek SN. Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. Int J Med Mushrooms. 2013;15(6):539-54. doi:10.1615/intjmedmushr.v15.i6.30 Researchers believe that improved hippocampus functioning may explain the reductions in anxious and depressive behaviors in mice receiving these extracts. However, the anticancer effects of lion’s mane mushroom have never been tested in humans, so more research is needed. Summary

Lion's mane has been researched for its health benefits stemming from plant compounds that may boost brain health, support immune health, and help fight depression and anxiety. To date, human studies have not found the side effects of lion's mane, which appears safe for consumption. Given that many lion's mane supplements are affordable, they may be worth trying. Always discuss new supplements with your medical provider before taking them. When should I take Lion's Mane supplements? Called ‘Yamabushitake’ in Japan meaning “those who sleep in the mountains” as named after Yamabushi Buddhist Monks – wandering ascetics from the Shugendō spiritual tradition who were thought to use Lion’s Mane to assist in meditation. UK-grown organic Reishi tincture, cloned in our lab and extracted in the tincture kitchen on our mushroom farm in Somerset. Dr. Watson takes a more conservative approach, recommending 250 to 500 milligrams up to three times a day with or without food. The brand she recommends, Om Organic Mushroom Nutrition, contains both mycelial biomass and the fruit body. Yi Z, Shao-Long Y, Ai-Hong W, Zhi-Chun S, Ya-Fen Z, Ye-Ting X, Yu-Ling H. Protective effect of ethanol extracts of Hericium erinaceus on alloxan-induced diabetic neuropathic pain in rats. Evid Based Complement Alternat Med. 2015;2015:595480. doi:10.1155/2015/595480Abdullah, N., Ismail, S. M., Aminudin, N., Shuib, A. S., & Lau, B. F. (2012). Evaluation of selected culinary-medicinal mushrooms for antioxidant and ACE inhibitory activities. Evidence-Based Complementary and Alternative Medicine, 2012

Chiu, C.-H., Chyau, C.-C., Chen, C.-C., Lee, L.-Y., Chen, W.-P., Liu, J.-L., ... Mong, M.-C. (2018, February). Erinacine A-enriched Hericium erinaceus mycelium produces antidepressant-like effects through modulating BDNF/PI3K/Akt/GSK-3β signaling in mice. International Journal of Molecular Sciences, 19(2), 341 Liu, J. H., Li, L., Shang, X. D., Zhang, J. L., & Tan, Q. (2016, May 13). Anti- Helicobacter pylori activity of bioactive components isolated from Hericium erinaceus [Abstract]. Journal of Ethnopharmacology, 183, 54–58

Li IC, Lee LY, Tzeng TT, et al. Neurohealth properties of Hericium erinaceus mycelia enriched with erinacines. Behav Neurol. 2018;2018:5802634. Published 2018 May 21. doi:10.1155/2018/5802634 Antioxidants are able to support the immune system by reducing the workload and preventing chronic inflammation, from which so many diseases spring. [7] Atherosclerosis Two major factors typically cause stomach ulcers: overgrowth of the bacteria H. pylori and damage to the mucous layer of the stomach that’s often due to long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) ( 17). Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats, (3)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852124/ Kim SP, Kang MY, Kim JH, Nam SH, Friedman M. Composition and mechanism of antitumor effects of Hericium erinaceus mushroom extracts in tumor-bearing mice. J Agric Food Chem. 2011 Sep 28;59(18):9861-9. doi: 10.1021/jf201944n

Additionally, animal studies have found that lion’s mane may help protect against Alzheimer’s disease, a degenerative brain disease that causes progressive memory loss. Tests have indicated that compounds from Lion’s Mane may support nerve impulse transmission as well as support short and long-term memory. Interestingly, the same compounds were found to counter oxidative stress on the brain. Samberkar, S., Gandhi, S., Naidu, M., Wong, K. H., Raman, J., & Sabaratnam, V. (2015). Lion's mane, Hericium erinaceus and tiger milk, Lignosus rhinocerotis (higher basidiomycetes) medicinal mushrooms stimulate neurite outgrowth in dissociated cells of brain, spinal cord, and retina: An in vitro study [Abstract]. International Journal of Medicinal Mushrooms, 17(11), 1047–1054 Kim SP, Nam SH, Friedman M. Hericium erinaceus (Lion's Mane) mushroom extracts inhibit metastasis of cancer cells to the lung in CT-26 colon cancer-tansplanted mice. J Agric Food Chem. 2013 May 22;61(20):4898-904. doi: 10.1021/jf400916cPotential antidepressant effects of a dietary supplement from the chlorella and Lion's mane mushroom complex in aged SAMP8 mice, (2)https://pubmed.ncbi.nlm.nih.gov/36118772/ While there are many causes of anxiety and depression, chronic inflammation could be a major contributing factor. Lion’s Mane is the most clinically studied of all the mushroom types which has driven its huge popularity throughout the West in recent years.