Teng, G.G.; Curtis, J.R.; Saag, K.G. Mortality and osteoporotic fractures: Is the link causal, and is it modifiable? Clin. Exp. Rheumatol. 2008, 26, S125–S137. [ Google Scholar] [ PubMed]

Kopelman, P.G. Obesity as a medical problem. Nature 2000, 404, 635–643. [ Google Scholar] [ CrossRef] Mirończuk-Chodakowska, I.; Witkowska, A.M.; Zujko, M.E. Endogenous non-enzymatic antioxidants in the human body. Adv. Med. Sci. 2018, 63, 68–78. [ Google Scholar] [ CrossRef] Pfeiler, G.; Königsberg, R.; Hadji, P.; Fitzal, F.; Maroske, M.; Dressel-Ban, G.; Zellinger, J.; Exner, R.; Seifert, M.; Singer, C.; et al. Impact of body mass index on estradiol depletion by aromatase inhibitors in postmenopausal women with early breast cancer. Br. J. Cancer 2013, 109, 1522–1527. [ Google Scholar] [ CrossRef][ Green Version] It's not like Milk & Honey London won't live on in other bars though. Satan's Whiskers, Happiness Forgets and Bar Swift are just a few London examples owned by ex-staff where you can see small nods (or big ones) to the old venue. Bulletin Place owned by Tim Philips is our closest part of the family in Sydney but there's plenty of ex-staff who are currently working in Australia – Darren Leaney is one example.Several artists have covered “Honey Bones,” paying homage to its enchanting melodies and timeless lyrics. These covers often interpret the song in unique ways, adding new dimensions to its meaning. 10. How does “Honey Bones” fit into Dope Lemon’s discography? Cheung, A.M.; Heisey, R.; Srighanthan, J. Breast cancer and osteoporosis. Curr. Opin. Endocrinol. Diabetes Obes. 2013, 20, 532–538. [ Google Scholar] [ CrossRef] [ PubMed]

Did It Work?: Not as I had hoped. I had a lot more energy and I wasn’t feeling constantly tired, but my pain didn’t decrease much. So I still think it works, but in a rather easy form of arthritis. Or if you have chronic joint pain without any clear diagnosis, you can try it. Tavafzadeh et al., through three separate studies, investigated the effects of jumping exercises in combination with honey supplementation on bone properties in young female rats [ 91– 93]. Each rat was subjected to the exercise for five minutes per day for five days per week. Tualang honey was orally supplemented to the rats at the dosage of 1 g/kg body mass/rat/day via force-feeding, 30 min prior to the jumping exercise for a duration of eight weeks [ 91, 92], while another study by the Tavafzadeh et al. [ 93] lasted for 8 and 16 weeks. From the first study, they found that the combination of honey and jumping exercise elicited more prominent beneficial effects on the tibial and femoral bone. This was shown by the increase in tibial wet and fat-free dry weights, tibial and femoral maximal load, tibial midshaft minimum diameter, and femoral midshaft maximum diameter compared to either jumping exercise or honey supplementation alone in young female rats [ 91]. In the second study with the same method, the combined regime significantly reduced bone resorption and enhanced antioxidant status indicated by lower serum C-terminal telopeptide of type 1 procollagen and higher serum total antioxidant status, respectively, but did not alter oxidative stress marker [ 92]. In the third experiment, Tavafzadeh et al. showed that continuous 16 weeks of combined jumping exercise and honey supplementation caused more beneficial effects on the tibial bone. This was evidenced by greater tibial maximum force, energy, proximal total bone density, proximal trabecular bone density, midshaft cortical bone density, cortical area, and midshaft cortical moment of inertia in the rats receiving combinational therapy as compared with individual therapy [ 93]. Moreover, the beneficial effects of the combinational therapy on the tibial bone properties could still be maintained even after eight weeks of cessation of exercise and supplementation [ 93]. Spilioti, E.; Jaakkola, M.; Tolonen, T.; Lipponen, M.; Virtanen, V.; Chinou, I.; Kassi, E.; Karabournioti, S.; Moutsatsou, P. Phenolic Acid Composition, Antiatherogenic and Anticancer Potential of Honeys Derived from Various Regions in Greece. PLoS ONE 2014, 9, e94860. [ Google Scholar] [ CrossRef] [ PubMed][ Green Version] Biggest Downside: I didn’t experience such a great relief as I did with turmeric supplements. In this case I used organic turmeric, but it’s a fact that our body doesn’t absorb the whole quantity of turmeric if you take it by mouth. That’s why every good supplement has a helper like bioperine.Manuka honey combined with α-cyclodextrin (Manuka Honey with Cyclopower™ (MHCP)) was developed to enhance the delivery of honey and improving its water solubility and stability [ 81, 82]. Katsumata et al. demonstrated that MHCP decreased the serum C-terminal telopeptide of type Ι collagen (a marker for bone resorption), femoral RANKL (stimulator of osteoclast formation), and nuclear factor of activated T-cells, cytoplasmic 1 mRNA expression (regulators of osteoclast formation) without any effect on uterine weight in ovariectomized mice. In addition, MHCP increased caecal bifidobacteria and bacteroid contents. These results suggested that the MHCP possesses prebiotic effects which potentiate the effects of honey by decreasing bone resorption in ovariectomized mice through suppressing inflammation [ 83]. Cianciosi, D.; Forbes-Hernández, T.Y.; Afrin, S.; Gasparrini, M.; Reboredo-Rodriguez, P.; Manna, P.P.; Zhang, J.; Bravo Lamas, L.; Martínez Flórez, S.; Agudo Toyos, P.; et al. Phenolic Compounds in Honey and Their Associated Health Benefits: A Review. Molecules 2018, 23, 2322. [ Google Scholar] [ CrossRef][ Green Version] Zaid, S.S.; Sulaiman, S.A.; Sirajudeen, K.N.; Othman, N.H. The effects of tualang honey on female reproductive organs, tibia bone and hormonal profile in ovariectomised rats—Animal model for menopause. BMC Complement. Altern. Med. 2010, 10, 82. [ Google Scholar] [ CrossRef] [ PubMed][ Green Version] van’t Hof, R.J.; Ralston, S.H. Cytokine-induced nitric oxide inhibits bone resorption by inducing apoptosis of osteoclast progenitors and suppressing osteoclast activity. J. Bone Miner. Res. 1997, 12, 1797–1804. [ Google Scholar] [ CrossRef]

Piredda, M.; Facchinetti, G.; Biagioli, V.; Giannarelli, D.; Armento, G.; Tonini, G.; De Marinis, M.G. Propolis in the prevention of oral mucositis in breast cancer patients receiving adjuvant chemotherapy: A pilot randomised controlled trial. Eur. J. Cancer Care 2017, 26, e12757. [ Google Scholar] [ CrossRef] Luchese, R.H.; Prudêncio, E.R.; Guerra, A.F.; Luchese, R.H.; Prudêncio, E.R.; Guerra, A.F. Honey as a Functional Food; IntechOpen: Rijeka, Croatia, 2017; ISBN 978-953-51-2880-9. [ Google Scholar] Honey Bones” served as a breakthrough hit for Dope Lemon, securing their presence in the indie music scene. Its lyrical depth and melodic allure set the tone for their subsequent releases. 11. What other songs by Dope Lemon are similar to “Honey Bones”?Anti-inflammatory properties of common phenolic compounds found in honey. 4. Effects of Honey on Animal Models of Osteoporosis 4.1. Normal Animals Tomasin, R.; Gomes-Marcondes, M.C.C. Oral administration of Aloe vera and honey reduces Walker tumour growth by decreasing cell proliferation and increasing apoptosis in tumour tissue. Phytother. Res. 2011, 25, 619–623. [ Google Scholar] [ CrossRef]