candidum extract would regulate the expression of AQP-5 in labial glands of SS patients and thereby promoted secretion of saliva to improve dry mouth symptoms [ 108]. The active polysaccharide fraction of the mucilage was determined to have an average molecular weight of ~10kDa for the ratio of glucoside to mannoside (~1:10) and the degree of acetylation (~35%). Therefore, in light of reported immunostimulating activities detailed below, Dendrobium plants could be promising therapeutic agents in the next decades.

brymerianum was evaluated and found to possess significant cytotoxicity against human non-small lung cancer H460 cells, showing 80% inhibition at a concentration of 50 µg/mL [ 31]. TDB inhibited epithelial-to-mesenchymal transition and sensitization of lung cancer cells to anoikis. Significantly decreased AQP-5 protein levels were observed after treatment with TNF-α 100 units/mL for 8hr, but was reversed by the pre-treatment of DP in a dose-dependent manner. DH-PS induced an anti-inflammatory molecule, IL-1ra, in mouse and human immune cells, especially monocytes. It significantly inhibited growth of lung cancer cell line A549 and suppressed growth factor-induced neovascularization.Investigations focused on polysaccharides from the stems of Dendrobium nobile led to the isolation of a pectic polysaccharide DNP-W5, which was composed of mannose, glucose, galactose, xylose, rhamnose and galacturonic acid in molar ratios of 3. Treatment with DO significantly attenuated serum levels of TC, TG, BUN and CREA, attenuated the electroretinogram deficits and pathological changes in the eyes of diabetic rats.

OHDA is a reactive oxidative species (ROS) producing agent which generates hydrogen peroxide, superoxide radical a hydroxyl radical involved in PD. Due to the high diversity of types of cancer, specific mechanisms of action have been explored to assign to Dendrobium spp. In a more recent study, it has been demonstrated that the reduction of migration and invasion of H292 cells by TDB was reduced by decreasing migration-regulating proteins, including integrins αv, α4, β1, β3 and β5, as well as activated focal adhesion kinase (pFAK), activated Ras-related C3 botulinum toxin substrate 1 (Rac1-GTP) and cell division control protein 42 (Cdc42) [ 29]. I am not needing my inhaler as often as I used to and there is a definite improvement in my breathing.DCP-H at the concentrations of 25 and 50 μg/mL provided slightly higher stimulation rate as compared to DCP-E, but there was no significant difference between them (p>0.

Aqueous solutions of DOP-W3-b were orally administered to mice once per day for 3 or 7 days, 500 mg/kg b. Furthermore, erianin induced cell apoptosis by activating both extrinsic (expression of downstream apoptotic protein Caspase-8) and intrinsic (Caspase-9) pathways. Convenient and Portable: The herbal supplement come in a compact and easy-to-carry bottle for convenient use on-the-go. Glutamate induced an inhibition of MTT reduction, while the 8,4'-oxyneolignane glucoside and (-)-syringaresinol-4,4'-bis- O- β-D-glucopyranoside showed neuroprotective activity at a concentration of 10 μM, with the relative protection of 25.

Moreover, the results indicate that treatment of diabetic rats with DO was effective in improving punctuate mechanical nociception, reduced hypoalgesia and histopathological changes of vital organs induced by hyperglycemia. officinale shows antioxidant effects, modulates some cytokines related to tumorigenesis, and induces apoptosis [ 56].

com/Regulation/Dendrobium-containing-Craze-pre-workout-supplement-hit-with-CA-class-action (Accessed May 23, 2012). A partial structure of DOP-1-1 is an O-acetylated glucomannan with β-D-configuration in pyranose sugar forms. Finance is provided by PayPal Credit (a trading name of PayPal UK Ltd, Whittaker House, Whittaker Avenue, Richmond-Upon-Thames, Surrey, United Kingdom, TW9 1EH). The hypoglycemic activities were based on the serum indices including blood glucose, glycosylated proteins and insulin levels, the changes in pathological morphology of the pancreas.sinense showed different degrees of cytotoxicity on SGC-7901, human hepatoma (BEL-7402) and chronic myelogenous leukemia (K562) cell lines. Nourish and purify-Penetrate layer by layer and repair gently,It can also help correct your immune system, reduce allergicreactions through desensitization therapy, andallergy. trimethoxy-5,4’-dihydroxybibenzyl (DTB), aloifoll and 5,3’-dihydroxy-3,4-dimethoxy-bibenzyl, along with a lignin glycoside longicornuol A, from D. Dendrobiums are sympodial epiphytic plants, which is a name they are worthy of, the name coming from Greek origin: "dendros", tree, and "bios", life.